ClINICAl NUTRITION AND COlORECTAl CANCER
نویسندگان
چکیده
Cachexia-anorexia syndrome, characterized by anorexia and loss of adipose tissue and skeletal muscle mass, is common feature in majority of patients with cancer, especially in cancer localized in gastrointestinal tract. Malnutrition is recognized as a negative prognostic factor in patients with colorectal cancer. Malnutrition in cancer patients reduces response to specific oncological therapy, slows down recovery after surgical treatment, leads to impairement of quality of life and decreases survival. It is considered that developement of cancer cachexia is a multifactorial process, however inflammation plays a major role. Therefore, targeting inflammation may represent an effective strategy to prevent/treat cachexia. Treatment should be patient-tailored and based on a multimodal approach.
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